@article {69,
	title = {Stretching DNA using the electric field in a synthetic nanopore},
	journal = {Nano Lett},
	volume = {5},
	year = {2005},
	month = {2005 Oct},
	pages = {1883-8},
	abstract = {<p>The mechanical properties of DNA over segments comparable to the size of a protein-binding site (3-10 nm) are examined using an electric-field-induced translocation of single molecules through a nanometer diameter pore. DNA, immersed in an electrolyte, is forced through synthetic pores ranging from 0.5 to 1.5 nm in radius in a 10 nm thick Si(3)N(4) membrane using an electric field. To account for the stretching and bending, we use molecular dynamics to simulate the translocation. We have found a threshold for translocation that depends on both the dimensions of the pore and the applied transmembrane bias. The voltage threshold coincides with the stretching transition that occurs in double-stranded DNA near 60 pN.</p>},
	keywords = {DNA, Nanotechnology, Static Electricity, Stress, Mechanical},
	issn = {1530-6984},
	doi = {10.1021/nl0510816},
	author = {Jiunn B Heng and Aleksei Aksimentiev and Chuen Ho and Patrick Marks and Yelena V Grinkova and S Sligar and Klaus Schulten and Gregory Timp}
}
